What the hell are Probiotics ?

Probiotic goodness of Avincia Gut Fuel Supplement

 The word “probiotics” in Greek literally means “For Life” and probiotics are a vital part of Avincia’s Gut Fuel supplement. Its formula includes four of the well-known probiotic bacterial strains that are proven to ensure your health and wellbeing in various ways. 

 What exactly are probiotics?

 

Probiotics are friendly microbes that give you numerous health benefits when you take them in satisfactory amounts [1]. Although microorganisms are often viewed in a bad light, there is an army of microbes, mostly bacteria, living in and on our bodies—mainly in our gut. They help us digest food, fend off pathogens, boost the immune system, and reduce inflammation. [1] While these organisms are generally helpful, a fraction of them can cause diseases.

 

A host of factors such as bad diets, lack of exercise, use of antibiotics, and age can cause imbalances in our gut microbiome composition, multiplying bad bacteria and diminishing good ones. These fluctuations can result in various disease conditions such as abdominal infections, digestive issues, inflammation, and even heart diseases. [2]

 

Probiotics have been found to help reverse these instabilities, restoring gut microbial balance, and thus improving health.

 

Avincia GUT Fuel Ingredients

 

Lactobacillus and Bifidobacterium as probiotics

 

Lactobacillus and Bifidobacterium are among the most common bacterial groups often used as probiotics in food preparations and dietary supplements [3]. Members of these groups perform extremely well as probiotics as they show high tolerance to harsh gut conditions such as high acid concentrations, gut enzymes, and bile acids [4][5][6][7].

They also have been studied extensively and their probiotic capabilities are well-documented.

 

Bifidobacterium animalis ssp lactis (HN019™)

 

This bacterial strain was first isolated from yogurt products and has been used in the preparation of fermented foods, beverages, and dietary supplements [4].

 

  1. animalis ssp lactis (HN019) was found to enhance immunity [8], fight pathogens such as E. coli and Salmonella [9][10][11], and help maintain the stability of the gut lining [12]. They also improve bowel habits, relieve constipation [13], and soothe gastrointestinal symptoms such as abdominal pain, vomiting, and flatulence [14].

 

Bifidobacterium animalis ssp lactis (DSM 15954) (BB-12®)

 

BB-12 is the most documented probiotic Bifidobacterium in the world, and for good reason [15]. It’s highly stable in food preparations such as freeze-dried powders and has numerous proven health benefits [15]. It has been shown to help maintain a healthy gut microbial population, enhance bowel function, protect against diarrhea, and boost immunity against illnesses such as respiratory tract infections [5][15]. 

 

Lactobacillus plantarum

 

  1. plantarum is a bacterial species that is commonly found in the human gut and in various fermented foods such as sauerkraut [16].

 

Various studies have reported that this bacterial species can act as a probiotic and bring about health effects such as lowering cholesterol levels [17], reduction of body fat percentage and obesity [18], and improving diabetic wound healing [19]. Other benefits include relieving constipation [20], fighting off intestinal pathogens [21], and preventing E. coli- induced diarrhea [22].

 

Lactobacillus rhamnosus

 

Lactobacillus rhamnosus (re-classified as Lacticaseibacillus rhamnosus) was initially isolated from healthy human fecal samples [23]. It is one of the widely studied bacteria for its probiotic potential.

 

The clinical benefits of L. rhamnosus are well documented. Among them are reduction of symptoms in patients with Irritable Bowel Syndrome [24][25]; inhibition of pathogens such as Candida, Salmonella, C. difficile, and Staphylococcus [26] [27] [28]; protection of the gut cells from the C. diff toxic compounds [28]; and reducing the duration and severity of antibiotic-associated diarrhea [29].

 

Are these bacterial strains safe to consume?

 

Absolutely, If you’re worried about the safety of these probiotic strains, there’s no need to. Most of these strains are found in fermented foods and among healthy gut flora.

 

Avincia Gut Fuel has been scientifically formulated to support Gastrointestinal Health and immune system function.

 

However, if you have any serious illnesses, it is wise to discuss with your doctor before taking any probiotic supplements.

 

References

 

[1]        M. Kechagia et al., “Health Benefits of Probiotics: A Review,” ISRN Nutr., vol. 2013, pp. 1–7, Jan. 2013, doi: 10.5402/2013/481651.

[2]        S. Carding, K. Verbeke, D. T. Vipond, B. M. Corfe, and L. J. Owen, “Dysbiosis of the gut microbiota in disease,” Microb. Ecol. Health Dis., vol. 26, no. 0, Feb. 2015, doi: 10.3402/MEHD.V26.26191.

[3]        World Gastroenterology Organisation Global Guidelines, “Probiotics and prebiotics,” no. February, 2017.

[4]        J. Cheng, A. Laitila, and A. C. Ouwehand, “Bifidobacterium animalis subsp. lactis HN019 Effects on Gut Health: A Review,” Front. Nutr., vol. 8, no. December, 2021, doi: 10.3389/fnut.2021.790561.

[5]        J. Flach, M. B. van der Waal, A. F. M. Kardinaal, J. Schloesser, R. M. A. J. Ruijschop, and E. Claassen, “Probiotic research priorities for the healthy adult population: A review on the health benefits of Lactobacillus rhamnosus GG and Bifidobacterium animalis subspecies lactis BB-12,” Cogent Food Agric., vol. 4, no. 1, 2018, doi: 10.1080/23311932.2018.1452839.

[6]        I. Pitino et al., “Survival of Lactobacillus rhamnosus strains in the upper gastrointestinal tract,” Food Microbiol., vol. 27, no. 8, pp. 1121–1127, 2010, doi: 10.1016/j.fm.2010.07.019.

[7]        M. C. de Vries, E. E. Vaughan, M. Kleerebezem, and W. M. de Vos, “Lactobacillus plantarum-survival, functional and potential probiotic properties in the human intestinal tract,” Int. Dairy J., vol. 16, no. 9, pp. 1018–1028, 2006, doi: 10.1016/j.idairyj.2005.09.003.

[8]        L. E. Miller, L. Lehtoranta, and M. J. Lehtinen, “The Effect of Bifidobacterium animalis ssp. lactis HN019 on Cellular Immune Function in Healthy Elderly Subjects: Systematic Review and Meta-Analysis,” Nutr. 2017, Vol. 9, Page 191, vol. 9, no. 3, p. 191, Feb. 2017, doi: 10.3390/NU9030191.

[9]        Q. Shu and H. S. Gill, “A dietary probiotic (Bifidobacterium lactis HN019) reduces the severity of Escherichia coli O157:H7 infection in mice,” Med. Microbiol. Immunol. 2001 1893, vol. 189, no. 3, pp. 147–152, Apr. 2001, doi: 10.1007/S430-001-8021-9.

[10]     Q. Shu et al., “Dietary Bifidobacterium lactis (HN019) Enhances Resistance to Oral Salmonella typhimurium Infection in Mice,” Microbiol. Immunol., vol. 44, no. 4, pp. 213–222, Apr. 2000, doi: 10.1111/J.1348-0421.2000.TB02486.X.

[11]     M. Ahmed, J. Prasad, H. Gill, L. Stevenson, and P. Gopal, “Impact of consumption of different levels of Bifidobacterium lactis HN019 on the intestinal microflora of elderly human subjects - PubMed,” J. Nutr. Heal. aging, vol. 11, no. 1, pp. 26–31, 2007, [Online]. Available: https://pubmed.ncbi.nlm.nih.gov/17315077/.

[12]     H. Putaala et al., “Effect of four probiotic strains and Escherichia coli O157:H7 on tight junction integrity and cyclo-oxygenase expression,” Res. Microbiol., vol. 159, no. 9–10, pp. 692–698, Nov. 2008, doi: 10.1016/J.RESMIC.2008.08.002.

[13]     A. Ibarra, M. Latreille-Barbier, Y. Donazzolo, X. Pelletier, and A. C. Ouwehand, “Effects of 28-day Bifidobacterium animalis subsp. lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled, and dose-ranging trial,” Gut Microbes, vol. 9, no. 3, pp. 236–251, May 2018, doi: 10.1080/19490976.2017.1412908/SUPPL_FILE/KGMI_A_1412908_SM1145.DOCX.

[14]     P. A. Waller et al., “Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults,” Scand. J. Gastroenterol., vol. 46, no. 9, pp. 1057–1064, Sep. 2011, doi: 10.3109/00365521.2011.584895.

[15]     M. Jungersen, A. Wind, E. Johansen, J. E. Christensen, B. Stuer-Lauridsen, and D. Eskesen, “The science behind the probiotic strain bifidobacterium animalis subsp. Lactis bb-12®,” Microorganisms, vol. 2, no. 2, pp. 92–110, 2014, doi: 10.3390/microorganisms2020092.

[16]     M. Fidanza, P. Panigrahi, and T. R. Kollmann, “Lactiplantibacillus plantarum–Nomad and Ideal Probiotic,” Front. Microbiol., vol. 12, no. October, pp. 1–13, 2021, doi: 10.3389/fmicb.2021.712236.

[17]     T. D. T. Nguyen, J. H. Kang, and M. S. Lee, “Characterization of Lactobacillus plantarum PH04, a potential probiotic bacterium with cholesterol-lowering effects,” Int. J. Food Microbiol., vol. 113, no. 3, pp. 358–361, Feb. 2007, doi: 10.1016/J.IJFOODMICRO.2006.08.015.

[18]     S. Jung et al., “Supplementation with two probiotic strains, Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032, reduced body adiposity and Lp-PLA2 activity in overweight subjects,” J. Funct. Foods, vol. 19, pp. 744–752, Dec. 2015, doi: 10.1016/J.JFF.2015.10.006.

[19]     M. Mohtashami, M. Mohamadi, M. Azimi-Nezhad, J. Saeidi, F. F. Nia, and A. Ghasemi, “Lactobacillus bulgaricus and Lactobacillus plantarum improve diabetic wound healing through modulating inflammatory factors,” Biotechnol. Appl. Biochem., vol. 68, no. 6, pp. 1421–1431, Dec. 2021, doi: 10.1002/BAB.2064.

[20]     F. Li et al., “Lactobacillus Plantarum CQPC05 Isolated from Pickled Vegetables Inhibits Constipation in Mice,” Appl. Sci. 2019, Vol. 9, Page 159, vol. 9, no. 1, p. 159, Jan. 2019, doi: 10.3390/APP9010159.

[21]     L. Y. Jessie Lau and F. Y. Chye, “Antagonistic effects of Lactobacillus plantarum 0612 on the adhesion of selected foodborne enteropathogens in various colonic environments,” Food Control, vol. 91, pp. 237–247, Sep. 2018, doi: 10.1016/J.FOODCONT.2018.04.001.

[22]     K. M. Yang, Z. Y. Jiang, C. T. Zheng, L. Wang, and X. F. Yang, “Effect of Lactobacillus plantarum on diarrhea and intestinal barrier function of young piglets challenged with enterotoxigenic Escherichia coli K88,” J. Anim. Sci., vol. 92, no. 4, pp. 1496–1503, Apr. 2014, doi: 10.2527/JAS.2013-6619.

[23]     moloko G. Mathipa-Mdakane and M. S. Thantsha, “Lacticaseibacillus rhamnosus : A Suitable Candidate for the Construction of Novel Bioengineered Probiotic Strains for,” Foods, vol. 11, p. 785, 2022.

[24]     N. Pedersen et al., “Ehealth: Low FODMAP diet vs Lactobacillus rhamnosus GG in irritable bowel syndrome,” World J. Gastroenterol., vol. 20, no. 43, p. 16215, Nov. 2014, doi: 10.3748/WJG.V20.I43.16215.

[25]     A. Horvath, P. Dziechciarz, and H. Szajewska, “Meta-analysis: Lactobacillus rhamnosus GG for abdominal pain-related functional gastrointestinal disorders in childhood,” Aliment. Pharmacol. Ther., vol. 33, no. 12, pp. 1302–1310, Jun. 2011, doi: 10.1111/J.1365-2036.2011.04665.X.

[26]     W. Mohammedsaeed, A. J. McBain, S. M. Cruickshank, and C. A. O’Neill, “Lactobacillus rhamnosus GG Inhibits the Toxic Effects of Staphylococcus aureus on Epidermal Keratinocytes,” Appl. Environ. Microbiol., vol. 80, no. 18, p. 5773, 2014, doi: 10.1128/AEM.00861-14.

[27]     M. Guo, C. Zhang, C. Zhang, X. Zhang, and Y. Wu, “Lacticaseibacillus rhamnosus Reduces the Pathogenicity of Escherichia coli in Chickens,” Front. Microbiol., vol. 12, p. 1217, Jun. 2021, doi: 10.3389/FMICB.2021.664604/BIBTEX.

[28]     E. Ephraim, R. D. Schultz, and N. Safdar, “Lactobacillus rhamnosus GG protects cells from Clostridium difficile toxins.,” Br. Microbiol. Res. Journal, vol. 3, no. 2, pp. 165–175, 2013.

[29]     H. Szajewska and M. Kołodziej, “Systematic review with meta-analysis: Lactobacillus rhamnosus GG in the prevention of antibiotic-associated diarrhoea in children and adults,” Aliment. Pharmacol. Ther., vol. 42, no. 10, pp. 1149–1157, Nov. 2015, doi: 10.1111/APT.13404.

 

Newer Post →



Leave a comment